No time to exercise? Take a pill instead.

We’ve got instant energy in a bottle, so why not exercise in a pill? Believe it or not, scientists are working on it. So far, the only bodies to benefit from the no-exercise pill belong to mice. But, the drug is currently being tested in humans as a therapy to help prevent complications of heart bypass surgery. Scientists hope that someday, the same drug may help people to gain the benefits of exercise without even breaking into a sweat.

The exercise-in-a-pill drug is composed of two compounds known as GW1516 and AICAR. Using mice as models, researchers have discovered that the compound GW1516 significantly boosts endurance in mice that were accustomed to exercising on a daily basis. In fact, given this substance, the little critters could run an average of 68% faster and 70% farther than their sedentary cousins. Oddly, sedentary mice treated to this chemical cocktail did not experience the same result. In fact, it had no effect at all.

AICAR, on the other hand, improved endurance in mice that didn’t care to shake a leg much. At the end of the experiment, these sedentary little guys ran 23% longer and a whopping 44% faster than they could prior to receiving the AICAR treatment. And, they did so without stepping up on time spent on the wheel. Apparently, the drug promotes the same benefits as aerobic exercise by mimicking the same chemical response.

Of course, it’s not yet clear if the same results can be extrapolated from mouse to man. And, if it is possible, the exercise-in-a-pill may be a long time coming before taking up residence in our medicine cabinets. But, why sit around and wait at all?

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